In the field of ceramic tool processing, the incorporation of solid lubricants into self-lubricating ceramic tools forms a supportive lubricating film during the cutting process, effectively enhancing the cutting performance of the tools. Concurrently, Nanofluid Minimum Lubrication Technology (NMQL), as an emerging lubrication method, holds the potential to improve tool performance. However, due to significant cutting forces, NMQL faces challenges in effectively reaching the machining area, thereby limiting its cooling and lubricating efficiency. To overcome this challenge, our study proposes an innovative strategy by combining self-lubricating ceramic tools with nanofluids, aiming to enhance ceramic tool performance through synergistic lubrication effects. We conducted experimental studies under various lubrication conditions, comparing the performance of self-lubricating ceramic tools with traditional ceramic tools in cutting operations. A comprehensive evaluation of parameters such as tool life, cutting temperature, and cutting forces was performed. The results demonstrate that self-lubricating ceramic tools enable more efficient penetration of nanofluids into the machining area. In comparison to sole nanofluid lubrication, the synergistic effect significantly improves tool performance while substantially reducing production costs. This research contributes to advancing the development and widespread application of self-lubricating ceramic tools in the field of mechanical processing.