In this research study, surface modification of Ti64 alloy was carried out using laser surface texturing (LST). The investigation aims to explore the effects of loads, oleophilic textured surfaces, and MoS 2 as a solid lubricant on the friction and wear reduction of Ti64 alloy and AISI 52100 steel tribo-pairs. Three types of LST textures (Circular, triangular, and square textures) were created on the Ti64 alloy. Subsequently, tribological experiments were performed using a ball-on-disc universal tribometer at loads of 5, 10, and 15N with a 15 Hz frequency. The worn surface was analyzed using various methods, including optical microscopy, 3D-profilometer, FESEM, EDAX analysis, and Raman spectroscopy. The study compared the coefficient of friction (COF) and wear behavior of non-textured surfaces (N TS) with those of textured surfaces (T S) under both dry sliding conditions (D SC) and lubricated sliding conditions (L SC). The results demonstrated a significant reduction in the COF and wear coefficients on the T S. Specifically, the circular texture (C iT) exhibited a remarkable reduction of 39.3%, 63.83%, and 83.6% in wear coefficients compared to the N TS tested under D SC and L SC (using pure PAO-4 and PAO-4 + 1% wt MoS 2) with sliding load of 15N. D SC showed abrasion, adhesion, and delamination wear, while L SC displayed mild adhesion, delamination, and tribo-layer formation on N TS and T S. The analysis indicated that the use of L ST and solid lubricant nanoparticles on a Ti64 alloy would result in improved service life and better endurance in cutting tools and tribo-mating parts.